By default, a Splash Page is displayed when a gallery is embedded at less than 100% x 100% and displayed in Small Screen Mode.
The Splash Page is not displayed in the iframe gallery as the gallery is actually embedded (at 100% x 100%) into the HTML page being loaded into the iframe.
If you use the standard embedding code and do not want to use a Splash Page, then you can set showSplashPage="NEVER" (in JuiceboxBuilder-Pro's 'Customize -> Splash Page' section).
(would like thumbs to be bigger?)
If using local images, you can set the dimensions of your gallery's thumbnails by clicking the 'Change Sizes...' button on the 'Images' tab. New thumbnails will be generated at the specified dimensions and the thumbWidth and thumbHeight configuration options will be set accordingly. For a Flickr gallery, just open your gallery's 'config.xml' file in a plain text editor and add entries such as thumbWidth="100" and thumbHeight="80" to the opening <juiceboxgallery> tag.
when I click on one of the thumbs the large image is restricted by the iFrame height.
A Juicebox gallery's dimensions do not change when clicking on a thumbnail image and it is not possible to treat the thumbnail page in Small Screen Mode like a Splash page (expanding the gallery on a thumbnail click).
It might be possible to achieve this (using the Juicebox-Pro API, CSS and JavaScript) but you may run into complications with the normal hide/show thumbnails and expand/close gallery functionality. You might need to use some variables to keep track of the expanded state of the gallery and the visibility of the thumbnails to avoid unnecessarily closing the gallery (via the toggleExpand() method) when a user clicks on a thumbnail whilst in expanded mode. It might become very complicated very quickly.
Perhaps the best option would be to disable the Splash Page (if you do not want to use it) and display the Expand Button (by setting showExpandButton="TRUE" in JuiceboxBuilder-Pro's 'Customize -> Lite' section) so that users can expand the gallery fullscreen by clicking the button. (Please note that the Expand Button is disabled when using an iframe. This is noted in Option #2 here.)