Topic: Small images look bad after automatic resize
There are two problems:
First, Juicebox is stripping the ICC Profile from the image (it doesn't do this to unresized images).
This is BAD. If there's a profile (and there should always be a profile), it needs to be honored. It may be true that some browsers are still in the stone age and don't support color management ... but that is no reason to enforce a lack of color management. Let's make the web actually work for visual artists. Please!
Also, the resized images look soft. This is a normal artifact of any image resize; the solution is to build in a sharpening algorithm (like Photoshop's "bicubic sharper" option ... which isn't perfect, but it's pretty good. And much better than nothing.)
In its current state I consider multiple image sizes to be unusable.